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Collagen: What It Is, Benefits, and Side Effects May 28, 2021 · Collagen supplements can be bought in a powdered format which is easily added to drinks. Collagen is the main protein in all the connective tissues in our bodies. Collagen supplements may improve the skin's appearance, strengthen bones, and prevent joint pain. Side effects of collagen supplements include allergic reactions and stomach upset. Collagen Peptides: MedlinePlus Supplements Mar 14, 2022 · Collagen peptides are made by breaking down whole collagen proteins into smaller pieces. When taken by mouth, collagen peptides seem to build up in the skin and cartilage. This might help improve some skin and joint conditions. Collagen peptides are used for aging skin and osteoarthritis. They are also used for osteoporosis, brittle nails ... Collagen: Uses, Side Effects, Interactions, Pictures, Warnings... Find patient medical information for collagen on WebMD including its uses, side effects and safety, interac...